A speedy method for simultaneous determination in tablet active content by NIR and UV-Vis spectrophotometry: Comparison of PLS-1 and ICA-ANN models

In this study, the NIR and UV-Vis spectroscopy methods, which are frequently used in pharmaceutical industry, were applied to environments where Paracetamol, Propyphenazone Caffeine active substances present, spectroscopic data obtained evaluated comparatively with ICA-ANN PLS-1, powerful chemometric methods. When using solid agents method, liquid solutions equivalent them method. Following application of both spectral as chemometrics methods method yielded more accurate results than PLS-1. High recovery rates relatively low standard deviations found recommended for use industry.